Celiac Disease can be RESTRICTIVE.

Celiac Disease Clinical Trials May Provide More Therapeutic Options!

Living with celiac disease can be restrictive.
Celiac disease is a serious autoimmune disease that causes damage to the small intestine when foods with gluten are consumed. Severe dietary restrictions (opting for gluten-free diets) can lead to feelings of loneliness, and anxiety.

This condition affects 1 in 100 people worldwide, but only about 30% are properly diagnosed. More research into celiac disease is sorely needed to reduce its burden. Revive Research Institute is conducting Clinical Trials in search of a new and potential celiac disease treatment that may be able to help people suffering from this condition.

You may be eligible to participate in the celiac disease clinical trials if you:

  • Are 18 years or older
  • Have a confirmed diagnosis of celiac disease
  • Have been on a gluten-free diet for at least 12 months
  • Don’t have any other inflammatory gastrointestinal disorder (like Crohn’s disease)

*Additional Criteria may apply

We are investigating potential treatment options for Celiac Disease that may be able to break down gluten from the foods in the small intestine. Participate today!

*Participation is free of cost. And insurance is not required. Study-related care will be provided at no cost.
*Participants will receive a stipend for their time and travel.

Please provide YOUR contact information only.

About the Celiac Disease Clinical Trials

At Revive Research Institute, we are investigating a new potential celiac disease treatment that may be able to help people who have been diagnosed with celiac disease. The Celiac Disease Clinical Trials is investigating the safety and effectiveness of a potential treatment option, designed to break down gluten in the stomach in comparison to a placebo in those with celiac disease who are on a gluten-free diet.

The study medication is being evaluated to see how well it reduces celiac-related symptoms and intestinal damage due to gluten exposure. The total duration of the study is 36 weeks and will require that the participant consumes the oral study medication 3 times per week. Throughout the study, those eligible to participate will have to consume small amounts of gluten, and participants will be monitored for any celiac disease-related symptoms.
To fulfill the initial participation criteria of the study, participants need to be 18 years or older, have a celiac disease diagnosis (confirmed by biopsy), must be on a gluten-free diet for at least 12 months, and must not have any inflammatory gastrointestinal disorders.

*Before participating in the study, the study team will provide you with all the information related to the study. At this time, we encourage participants to ask as many questions as they’d like. Once you are satisfied and have all your questions about the study answered, you will be asked to sign an Informed Consent Form.
*Participation is completely voluntary. You can leave the study at any time.

Get Started: What to Expect?

If you are interested in participating in the Celiac Disease Clinical Trials, fill the form above. Someone from the study team will contact you and ask you questions related to your health and answer any questions you may have about participating. If you decide to participate and are eligible, you may be asked to sign an Informed Consent Form. The form will include all the information about the study and the study team will also discuss it in detail with you about the study.

The study lasts for 36 weeks for each participant and you may be asked to visit the study site at least 7 times throughout the duration of the study. The study medication will be administered orally. Throughout the study, you may have to undergo certain tests and procedures, to measure your progress. You might either receive the study drug or the placebo, along with study snack bars. Neither you nor the study team will know which group you might be placed in. You may be required to consume small amounts of gluten throughout the study. However, you will be monitored by the study team and doctor for any side effects from this gluten exposure.

*Participation is free. You will receive all study-related care including the study medication and tests and procedures, free of cost. 

Age

18 years or older

Condition

Celiac Disease

Location

Michigan

About Celiac Disease & Gluten Sensitivity

Celiac disease also known as gluten-sensitive enteropathy is a genetic condition that occurs when the body’s immune system attacks the cells in the small intestine (villi) during gluten exposure. This condition is known to affect approximately 2 million Americans.

For some people with celiac disease, exposure to small amounts of gluten can cause damage and inflammation in the small intestine. However, inflammation is not just restricted to the small intestine, it can occur anywhere in the body. For some people who have celiac disease, inflammation and damage can occur despite not having any symptoms.

Gluten is a protein found in wheat, rye, and oats. One of the components in gluten, also known as prolamin fractions causes problems for people with celiac disease.
Living with celiac disease can be crippling and restrictive due to the severe dietary restrictions associated with this condition.

Frequently Asked Questions (FAQs)

What is enteropathy?

Enteropathy is the damage and irritation in the small intestine. Celiac disease is usually the most common cause of enteropathy.

Why do I need to be exposed to gluten in this study?

Simply put, we won’t know how effective the investigational medication is until it is not tested with gluten exposure. This method of exposure has been used in research for decades.

How is celiac disease treated?

There is no permanent cure for celiac disease. If you have been diagnosed with celiac disease, the best way to work with this condition is the stay on a strict gluten-free diet. This means avoiding all foods that contain gluten.