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Flushed, Flustered, or Just Hot Flashes?

Hot Flashes Clinical Trials May Be An Option!

Vasomotor symptoms or hot flashes are most commonly experienced by women during menopause. Although the exact cause of it is not fully understood, studies suggest that it may occur due to changes in the hypothalamus.

If you or someone you know have vasomotor symptoms associated with menopause, Revive Research Institute is conducting Hot Flashes Clinical Trials that may provide potential treatment options.

To participate in the Hot Flashes Clinical Trials you must:

  • Be 40 to 65 years old
  • Not have had a menstrual period for at least 6 months
  • Experience hot flashes associated with menopause

*Additional Criteria may apply.

Revive Research Institute is conducting a clinical trial in search of a potential hot flashes treatment option. We are researching a non-hormonal, investigational medication that may be able to help women going through menopause and its associated symptoms.

*Participation in the Hot Flashes Clinical Trials is free of cost. To learn more or to enroll, fill out the form and someone from the research team will contact you to discuss if you may be eligible to participate in the study.

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Hot Flashes Clinical Trials

About the Hot Flashes Clinical Trials for Postmenopausal Women

We’re conducting a phase III clinical trial for postmenopausal women with vasomotor symptoms. The goal of the study is to test out the safety and efficacy of a non-hormonal hot flashes treatment (investigational) that may be able to help reduce vasomotor symptoms in women going through menopause.

The study is investigating a potential non-hormonal hot flashes treatment option that acts on the hypothalamus and may reduce the severity of the symptoms associated with menopause. The study medication is a capsule (oral route of administration). Participation in the clinical trial may last up to 9 to 15 months. Since this is a placebo-controlled clinical trial, participants may either receive the placebo (a drug with no active ingredient) or the study drug.

If you are eligible for the study and decide to participate, you may need to attend a few clinic visits which may include physical examinations, blood draws, and questionnaires. A dedicated research team including doctors and nurses will monitor your health throughout the study. Participation in the clinical trial is completely voluntary and you may withdraw at any time for any reason.

*Insurance is not a requirement to participate. Participants will receive study-related care completely free of cost.
*To participate, fill out the form above and one of our research staff will contact you to see if you may be eligible for the study. They may ask you a few questions related to your health and medical history to see if you may be eligible.

Get Started: What to Expect?

Participation in the study may last up to 9 to 15 months. If you are eligible and do decide to participate, you will either be given to study drug or a placebo. The study drug or placebo is a capsule and will be taken once or twice daily. Neither you nor the study doctor will know which medication you receive. The study team will provide complete information regarding the hot flashes clinical trials and the study medication before you participate, in the Informed Consent process.

There may be 11 clinic visits for the study and a few telephone calls. The study team will discuss all the details of the study’s visits during the Informed Consent process. Participation in the clinical trial is completely voluntary. You are free to withdraw at any time for any reason. Insurance is not a requirement to participate. And all participants may receive compensation for their time and travel during the study.

Throughout the study, while you are taking the medication, your health will be monitored by a qualified research team, including doctors and nurses. We encourage all participants to ask as many questions as they’d like before deciding to participate in any research study.


40 to 65 years old


Hot Flashes (Postmenopause)



Hot Flashes: The Aftermath of Menopause

Hot Flashes

Vasomotor symptoms also known as hot flashes are a very common symptom of menopause. Hot Flashes are unusual increases in the body temperature that occurs periodically. About 75% of all women have these sudden, brief, periodic increases in their body temperature.

Women who experience vasomotor symptoms may have:

  • A sudden feeling of warmth, especially through the face, neck, and chest
  • A flushed appearance
  • Rapid heartbeat
  • Sweating, primarily on the upper body

Hot flashes may be so intense that they soak through nightclothes and bed sheets. Vasomotor symptoms are not related to the temperature of your bedroom, or how much clothing you are wearing. Doctors do not understand its exact cause, however, researchers believe that it may occur due to changes in the hypothalamus (a part of the brain that regulates body temperature). The frequency and severity of the hot flashes can vary for every woman. Some can be bearable, some can be irritating and others can be debilitating.

Most women experience hot flashes for 6 months to 2 years, whereas, a few can experience them for years. For a very small portion of women, it may never go away. There is no way to predict when hot flashes may start or stop.

Frequently Asked Questions (FAQs)

1. How long does menopausal hot flashes last?

Hot flashes may last anywhere between 6 months to 2 years. For some women, they last for years, and for others, the vasomotor symptoms never go away.

2. What is menopause?

Menopause is the time after 12 months since a woman stops receiving her menstrual period. This period usually begins between 40 to 55 years of age for most women.

3. How long will the study last?

The hot flashes clinical trials may last somewhere between 9 to 15 months. The study team will provide you with details of the study, including the duration of the study and the number of visits that may occur.

4. How will the study drug be administered?

The study drug will be administered orally, through a capsule. The study staff will provide eligible participants who decide to participate with details of the study drug, when it may be consumed, and how many times a day.

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Revive Research Institute, Inc.

28270 Franklin Road
Southfield, MI

T: 248-564-1485