Depression: More than Just a Bad Mood

Know Your Condition and the Options Available To Help Your Mind. Clinical Trials for Major Depressive Disorder Might Help!

Depression (Major Depressive Disorder) is a medical condition that negatively impacts a person’s emotions, the way they feel and behave. Despite recent advances in medical science, depression is still frequently left untreated. There is a dire need for more effective treatment options.

Currently, psychiatrists near you at select centers in the USA, including our sites in Revive Research Institute, are enrolling participants in clinical trials for Major Depressive Disorder.

Anyone matching the following criteria may be eligible for our Depression Clinical Trials:

  • Male or female between 18 to 60 years of age
  • Currently having Major Depressive Disorder
  • Currently on a stable dose of systemic oral antidepressant medication

We are currently conducting Phase 2, Major Depressive Disorder Clinical Trials on an experimental drug that may be able to help with your symptoms of Depression. If you are interested in participating for a brighter tomorrow, please fill the form. Your participation is completely voluntary and you are free to leave at any time.
*Participants who are eligible and decide to participate, receive study-related care and treatment free-of-cost. No insurance is required.

Please provide YOUR contact information only.
major depressive disorder Depression Clinical Trials

About Major Depressive Disorder Study

A total of 320 men and women will be enrolled in the clinical trials for major depressive disorders. On the basis of the treatment method, subjects will be divided into two groups. Each participant will be in the study for 98 days, with a 28-day screening period, 42-days of double-blind treatment, and 3-4 weeks of follow-up.

This is a Phase 2 double-blind, placebo-controlled trial that will take place in about 50 study centers in the United States. It’s a fixed-dose clinical trial that compares the study drug versus a placebo to see how safe and effective it is. Throughout the Depression Clinical Trials, neither you, nor the study doctor will know which medication you receive i.e. the study drug or the placebo (without the active ingredient). In the case of an adverse event, the doctor will know which drug you receive.

Males and females between the ages of 18 and 64 who have been diagnosed with Major Depressive Disorder are eligible to enroll in Depression Clinical Trials. The purpose of the study is to determine the safety and efficacy of the experimental drug taken orally in people with major depressive disorder for symptom reduction. Throughout the trial, data on adverse events, clinical laboratory results, ECG findings, and vital signs will be recorded to evaluate the drug’s tolerability.

What to Expect?

If you are suffering from and wish to be a part of the Major Depressive Disorder study, please reach out to us by filling the form above. Our representative will call you to see if you are a fit for this study.

Once that is established, you will be asked to sign an Informed Consent Form (ICF).  Once you’ve signed the ICF, you will be invited for a screening visit to our clinical site; this will be an introductory visit. After that, you will be taken through a series of health-related questions and tests to confirm your eligibility as a participant.

Now that your eligibility for this study is confirmed, you will formally be a part of this study which will be approximately 10 weeks. During this time, you will be provided with the study drug which you have to take orally.

There is no cost of participating and a team of highly qualified and experienced staff will provide you with study-related care for the duration of this study.

Length of study:

10 weeks

No. of Study Visits:

9 Visits



About Major Depressive Disorder

depression clinical trials

Depression is a type of mood disturbance characterized by a continuous sense of despair and a loss of interest. It affects how you feel, think, and behave and can lead to a number of mental and physical complications. It’s also known as Major Depressive Disorder or Clinical Depression.

Symptoms of depression

Appetite changes that aren’t specifically diet related, increased restlessness followed by insomnia, fatigue or lack of motivation to do day-to-day simple tasks, feelings of worthlessness or regret for previous mistakes. Not only that, problems concentrating due to challenges with clear thinking are all symptoms of MDD that distinguish it from sadness.

Complications of depression

Depression is a serious illness that can have devastating effects on you and your family. If you don’t manage depression, it will likely get worse. Here are some examples of depression complications which includes, misuse of alcohol or drugs, panic disorders, social phobia and even suicidal thoughts.

Causes of Depression

The root cause of Major Depressive Disorder symptoms vary from person to person. However, some common triggers include the loss of a loved one, relationship issues, major life changes such as work relocation, and physical, sexual or emotional abuse.


1. Why are women more likely to get depression?

Women are twice as likely as males to suffer from depression. One factor could be the many hormonal shifts that women go through. Depression is frequent during pregnancy and menopause, as well as after giving birth, having a miscarriage and during Pre-menstrual syndrome

2. How is Depression diagnosed?

The first step would be to consult your doctor. Some conditions and medications can mimic the symptoms of depression. Your doctor will rule out these conditions by running physical examinations, interview questions and lab tests. Once the doctor confirms that this is not due to a medical condition, he or she will either advise treatment options or refer to a mental health professional.

3. How do I know I'm developing the symptoms of depression?

Although depression expresses itself differently in each individual, there are certain similar indications and symptoms. Symptoms are:

  • Depressed mood
  • Loss of interest in daily activities
  • Changes in appetite and sleep patterns
  • Easily irritable
  • Feeling tired all the time
  • Anxiety

4. Do I have to pay to participate in Depression Clinical Trials?

Participation in our Clinical Trials for Major Depressive Disorder is free of cost to both you and your private insurance. If you qualify and decide to participate, you will be financially compensated for your time and travel. Details of the stipend will be given to you once you complete the screening process and move on to the Informed Consent Process.