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Depression: More than Just a Bad Mood

Know Your Condition and the Options Available To Help Your Mind. Clinical Trials for Major Depressive Disorder Might Help!

Depression (Major Depressive Disorder) is a medical condition that negatively impacts a person’s emotions and the way they feel and behave. Despite recent advances in medical science, depression is still frequently left untreated. There is a dire need for more effective treatment options.

Currently, psychiatrists near you at select centers in the USA, including our sites in Revive Research Institute, are enrolling participants in clinical trials for Major Depressive Disorder.

Anyone matching the following criteria may be eligible for our Depression Clinical Trials:

  • Male or female who are 18 years or older
  • Currently having Major Depressive Disorder
  • Additional Criteria may apply

We are currently conducting multiple Phase 2 & 3, Major Depressive Disorder Clinical Trials on novel therapies that may be able to help with your symptoms of Depression. If you are interested in participating for a brighter tomorrow, please fill out the form. Your participation is completely voluntary and you are free to leave at any time.
*Participants who are eligible and decide to participate, receive study-related care and treatment free of cost. Insurance is not a requirement.

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major depressive disorder Depression Clinical Trials

About Major Depressive Disorder Study

At Revive Research Institute, we are conducting multiple Phase 2 and Phase 3 Major Depressive Disorder Clinical Trials. The purpose of these Clinical Trials is to test out the safety, efficacy, and tolerability of novel treatment options that could potentially help people with their symptoms of Major Depressive Disorder.

Many of our research studies are double-blind and placebo controlled. Such trials compare the study drug with placebo to see how safe and effective it is. Neither you nor the study doctor will know which medication you receive i.e. the study drug or the placebo (without the active ingredient). In the case of an adverse event, the doctor will know which drug you receive.

Males and females who are 18 years or older and, have been diagnosed with Major Depressive Disorder are eligible to enroll in Depression Clinical Trials. The purpose of our multiple MDD Research Studies is to determine the safety and efficacy of the investigational product taken orally. Throughout the trial,  the study team will record data on adverse events, clinical laboratory results, ECG findings, and vital signs to evaluate the drug’s tolerability.

What to Expect?

If you are suffering from Depression and would like to participate in our Major Depressive Disorder studies, please reach out to us by filling out the form above. One of our study team representatives will call you to see if you are a fit for this study (pre-screening).

Someone from the research team will ask you to sign an Informed Consent Form (ICF) if you meet the study criteria during the pre-screening process. Once you sign the ICF, we will invite you for a screening visit to our clinical site; this will be an initial visit. After that, you will undergo a series of health-related questions and tests to confirm your eligibility as a participant.

Once you receive confirmation of eligibility, you will formally be a part of any one of the Major Depressive Disorder Research Studies. You will receive all the information about the research study you might enroll in during the ICF process. We encourage you to ask as many questions as you would like before deciding to participate.

There is no cost to participating and a team of highly qualified and experienced staff will provide you with study-related care for the duration of this study.

Length of study:

10 – 64 weeks

No. of Study Visits:

8 – 12 Visits



About Major Depressive Disorder

depression clinical trials

Depression is a type of mood disturbance characterized by a continuous sense of despair and a loss of interest. It affects how you feel, think, and behave and can lead to a number of mental and physical complications. It’s also known as Major Depressive Disorder or Clinical Depression.

Symptoms of depression:

Symptoms include appetite changes, an increase in restlessness following insomnia, fatigue or lack of motivation to do day-to-day simple tasks, and feelings of worthlessness or regret. Not only that, problems concentrating due to challenges with clear thinking.

Complications of depression

Depression is a serious illness that can have devastating effects on you and your family. If you don’t manage depression, it will likely get worse. The complications of depression include, misuse of alcohol or drugs, panic disorders, social phobia, and even suicidal thoughts.

Causes of Depression

The root cause of Major Depressive Disorder symptoms varies from person to person. However, some common triggers include the loss of a loved one, relationship issues, major life changes such as work relocation, and physical, sexual, or emotional abuse.


1. Why are women more likely to get depression?

Women are twice as likely as males to suffer from depression. One factor could be hormonal shifts that women go through. Depression is frequent during pregnancy and menopause, as well as after giving birth, having a miscarriage, and during pre-menstrual syndrome.

2. How is Depression diagnosed?

The first step would be to consult your doctor. Some conditions and medications can mimic the symptoms of depression. Your doctor will rule out these conditions by running physical examinations, interview questions, and lab tests. Once the doctor confirms that this is not due to a medical condition, he or she will either advise treatment options or refer to a mental health professional.

3. How do I know I'm developing the symptoms of depression?

Although depression expresses itself differently in each individual, there are certain similar indications and symptoms. Symptoms are:

  • Persistent sadness
  • Loss of interest in daily activities
  • Changes in appetite and sleep patterns
  • Irritability
  • Fatigued
  • Anxiety

4. Do I have to pay to participate in Depression Clinical Trials?

Participation in our Clinical Trials for Major Depressive Disorder is free of cost to both you and your private insurance. If you qualify and decide to participate, you will be financially compensated for your time and travel. Details of the stipend will be given to you once you complete the screening process and move on to the Informed Consent Process.

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Revive Research Institute, Inc.

28270 Franklin Road
Southfield, MI

T: 248-564-1485