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Suffering From Eosinophilic Esophagitis?

Clinical Trials May Be An Option!

Eosinophilic Esophagitis (EoE) more commonly known as Allergic Esophagitis is a painful condition where the esophagus becomes inflamed due to the presence of certain allergens. Due to this inflammation, the esophagus does not contract properly leading to difficulty in swallowing, heartburn, abdominal pain and vomiting.  If left untreated, the esophagus can narrow and develop rings or abscesses.

You are at a greater risk for developing this condition if you have Atopic dermatitis, asthma or food or environmental allergies.

Despite available medications, there is an unmet need to find a potential Eosinophilic Esophagitis treatment. If you meet the eligibility criteria mentioned below, there might be a potential treatment option for your condition.

Participation Criteria:

  • Are 18 years of age or older
  • Diagnosed with Eosinophilic Esophagitis (EoE)
  • Can comply with study medication and procedure

We, at Revive Research Institute, are conducting a Phase 2 Gastroenterology Clinical Trials with the goal of assessing the long term effects of a study drug that may help in the treatment of Esophagitis in people diagnosed with Active Eosinophilic Esophagitis (EoE).

*To participate, please fill the online form. Participation in any of our Clinical Trials including the Eosinophilic Esophagitis Clinical Trial is free of cost to you. You DO NOT have to pay to participate. Insurance is not required.

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Eosinophilic Esophagitis gastroenterology Research

About the Eosinophilic Esophagitis Study

This is a Phase 2 double-blinded, placebo-controlled study that assesses the efficacy, safety and tolerability of the study drug that may be used as an experimental Eosinophilic Esophagitis treatment. This means that you might either receive the experimental drug or a placebo (drug without the active ingredient).

If you decide to participate and qualify for the research, the study doctor will not know which medication you receive as this is a double-blinded study. There is a 50% chance that you might receive the placebo or the study treatment. In the case of an adverse event, the study doctor will be notified of which treatment you receive.

The purpose of the study is to find how EoE responds to the study drug and to learn how it can help those people who are diagnosed with EoE. Approximately 50 patients will be enrolled in the study and the total duration of the study would be around 14 weeks.

Participation in the study will be completely voluntary. If you are 18 years or above and diagnosed with EoE this study might help you to alleviate EoE symptoms.

Get Started: What to Expect?

Eosinophilic Esophagitis (EoE) is a chronic and progressive disease of the immune system resulting in damage to the esophagus with loss of function resulting in difficulty swallowing. Eosinophilic Esophagitis is caused by the presence of large numbers of eosinophils in the esophagus.

If you are suffering from and wish to be a part of the EoE study, please reach out to us by filling the form. Someone from our research team will reach out to you via a call to tell you the process of enrolling and determine whether you’re a suitable fit for the EoE Clinical Trials.

There are currently no therapies approved by the FDA for EoE. If you qualify to participate in our Clinical Trial, you will be asked to sign an Informed Consent Form. This form includes all the information about the study. Multiple blood tests and study-related assessments will be done and you will be provided a daily questionnaire to complete during the study. If you qualify and decide to participate, you may receive the potential Eosinophilic Esophagitis treatment. The study medication will be given to you via injection into a vein in your arm.

Duration of the Study

98 days (14 weeks)

Number of study visits

6 Visits

Long term follow up


About Eosinophilic Esophagitis (EoE)

Eosinophilic Esophagitis (EoE) is a long-term immune system disorder in which a kind of white blood cell accumulates in the lining of the tube that links the mouth and the stomach. The esophagus tissue can become inflamed or injured as a result of this accumulation, which can make swallowing difficult or cause food to become lodged in the throat.


  • Swallowing problems (Dysphagia).
  • After swallowing, food becomes lodged in the esophagus (Impaction).
  • Pain in the center of the chest that does not react to antacids.
  • Food that hasn’t been digested is leaking back into circulation (Regurgitation).

Common Risk Factors:

  • Climate Change: People who live in cold or dry areas tend to be diagnosed with Eosinophilic Esophagitis.
  • Gender Preference: Males are more likely than females to have Eosinophilic Esophagitis.
  • Allergies Associations: People are more likely to be diagnosed with Eosinophilic Esophagitis if they have food or environmental allergies, asthma, or a chronic respiratory condition.


  • Esophagus becomes scarred and narrowed. This makes swallowing more difficult and increases the chances of food being trapped.
  • Some people experience gagging when food becomes trapped in their throat which can result in the tearing of the esophagus.

Frequently Asked Questions (FAQs)

Who can treat Eosinophilic Esophagitis (EoE)?

People diagnosed with Eosinophilic Esophagitis are treated by Gastroenterologists. Gastroenterologists are gut and stomach/bowel specialists. Since EoE is a gut-related condition, these are usually handled by Gastroenterologists.

Is it common for a person with Eosinophilic Esophagitis (EoE) to have other allergies?

Yes. Around 75% of the people who have EoE also have additional allergy disorders such allergic rhinitis or asthma. Some persons with EoE have discovered that symptoms occur exclusively when they are exposed to pollen in the spring.

Is Eosinophilic Esophagitis (EoE) rare?

EoE is an uncommon occurrence. However, because it is a relatively new condition, an increasing number of people are being diagnosed with it.

Where will the EoE Clinical Trial take place?

Our EoE Clinical Trials will take place on one of our study sites based in Michigan. The study site will be within a 50-mile radius location. If you qualify and decide to participate in the Clinical Trials, you will receive a stipend for your time and travel allowance for your convenience. You will also receive the potential Eosinophilic Esophagitis treatment i.e. study medication free of cost to you and your insurance.

Is it safe for my child to participate in the EoE Clinical Trials?

The EoE Clinical Trials are for people who are 18 years or older. Unfortunately, we are currently not enrolling participants less than 18 or those who are children. However, if you would like to enroll your child in future studies, please feel free to contact us or fill the form above.

What triggers Eosinophilic Esophagitis?

The presence of a large number of eosinophils in the esophagus causes eosinophilic esophagitis. Many factors, including immunological hypersensitivity reactions to specific foods or environmental proteins (allergens) in some susceptible persons, can trigger the development and buildup of eosinophils. People with chronic allergy conditions such as asthma or respiratory conditions may be susceptible to EoE.

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Revive Research Institute, Inc.

28270 Franklin Road
Southfield, MI

T: 248-564-1485